Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 10/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
| ▸ | PDE6A | P16499 | 1/20 | 0.31 |
| ▸ | PDE6G | P18545 | 1/20 | 0.31 |
| ▸ | PDE6B | P35913 | 1/20 | 0.31 |
| ▸ | PDE6C | P51160 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305945 | 0.94 | HPSE (0.36) | HPSEPDE5APDE4APDE4BPDE4C | |
| SCHEMBL9304064 | 0.83 | HPSE (0.36) | HPSEPDE5APDE4APDE4BPDE4C | |
| SCHEMBL9304057 | 0.77 | HPSE (0.36) | HPSEPDE5APDE4APDE4BPDE4C | |
| SCHEMBL10333342 | 0.75 | LMNA (0.39) | PDE5ATLR8LMNAENPP1HPGD | |
| SCHEMBL15702514 | 0.72 | HPGD (0.44) | TLR8LMNAHPGD | |
| SCHEMBL211457 | 0.70 | AMY1A (0.45) | AMY1A | |
| SCHEMBL9304660 | 0.69 | CA9 (0.36) | HPSETLR8EGFRENPP1MCHR1 | |
| SCHEMBL9306389 | 0.69 | STING1 (0.37) | HPSETLR8LMNAMAPK1EGFR | |
| SCHEMBL11397912 | 0.69 | HPGD (0.42) | TLR8LMNAMAPK1HPGD | |
| SCHEMBL10834059 | 0.68 | GAA (0.40) | AMY1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |