Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005311 | 0.85 | ALDH1A1 (0.42) | LMNAALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL13575314 | 0.81 | ALDH1A1 (0.40) | LMNAALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL7069218 | 0.81 | LMNA (0.48) | LMNA | |
| SCHEMBL3253895 | 0.77 | ALDH1A1 (0.37) | ALDH1A1TSHRCYP2D6CYP2C19MAPT | |
| SCHEMBL17716869 | 0.76 | ALDH1A1 (0.36) | LMNAALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL1520965 | 0.76 | ALDH1A1 (0.48) | LMNAALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL3277686 | 0.76 | ALDH1A1 (0.41) | LMNAALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL14556965 | 0.75 | ALDH1A1 (0.38) | LMNAALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL1521277 | 0.74 | LMNA (0.39) | LMNATHRB | |
| SCHEMBL17468382 | 0.74 | ALDH1A1 (0.41) | LMNAALDH1A1TSHRCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332852-A | Forming silyloxy unsaturated compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-26 | — | — | US | disclosed |