Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ACP1 | P24666 | 1/20 | 0.52 |
| ▸ | ILK | Q13418 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996770 | 0.87 | POLB (0.47) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL10791860 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL10791872 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL4584286 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL12799099 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL1747940 | 0.80 | MEN1 (0.59) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL686784 | 0.80 | ALDH1A1 (0.76) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL28217860 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL10271483 | 0.78 | NPC1 (0.56) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL13341104 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105949147-B | A kind of method of green syt 2-mercaptobenzothiazole analog derivative | 内蒙古工业大学 | 2018-10-19 | — | — | CN | disclosed |
| CN-105949147-A | Green synthesis method of 2-mercaptobenzothiazoles derivatives | 内蒙古工业大学 | 2016-09-21 | — | — | CN | disclosed |
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0161220-B1 | PROCESS FOR THE PREPARATION OF BETA-(BENZOTHIAZOLYLTHIO) AND BETA (BENZIMIDAZOLYLTHIO)CARBOXYLIC-ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-08-14 | — | — | EP | disclosed |
| EP-0129506-B1 | HETEROCYCLICALLY SUBSTITUTED THIO(CYCLO)ALKANE POLYCARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| US-4652653-A | Process for the preparation of β-(benzothiazolylthio)- and β-(benzimidazolylthio)-carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
| US-4612378-A | Process for the preparation of β-(benzothiazolylthio)- and β-(benzimidazolylthio-carboxylic acids | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0161220-A2 | Process for the preparation of beta-(benzothiazolylthio) and beta (benzimidazolylthio)carboxylic-acid derivatives | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |
| EP-0126030-A2 | Process for the preparation of beta-(benzothiazolylthio) and beta-(benzimidazolylthio) carboxylic acids | CIBA-GEIGY AG (CH) | 1984-11-21 | — | — | EP | disclosed |