Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
| ▸ | ILK | Q13418 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210763 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL12799099 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL4584286 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL686784 | 0.79 | ALDH1A1 (0.76) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL9305987 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL1747940 | 0.79 | MEN1 (0.59) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL11173803 | 0.78 | MAPT (0.56) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10220041 | 0.76 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL10271483 | 0.76 | NPC1 (0.56) | ALDH1A1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL13341104 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101863-B | Method for synthesizing benzothiazole-2-ketone derivative by using carbonyl sulfide and disulfide as raw materials | 内蒙古工业大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-108101863-A | It is a kind of using carbonyl sulfur and disulphide as the method for Material synthesis benzothiazole -2- ketones derivants | 内蒙古工业大学 | 2018-06-01 | — | — | CN | disclosed |