SCHEMBL9306044

SCHEMBL9306044

Nc1ccc2nc(S)oc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.58
RAB9A P51151 8/20 0.58
SMN1; SMN2 Q16637 7/20 0.58
KDM4E B2RXH2 6/20 0.58
ALDH1A1 P00352 5/20 0.58
MAPT P10636 5/20 0.58
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
HPGD P15428 3/20 0.58
GLA P06280 1/20 0.58
GAA P10253 1/20 0.58
PIK3CG P48736 1/20 0.43
GFER P55789 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
USP2 O75604 1/20 0.41
MAPK10 P53779 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
PLAU P00749 1/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9188510 0.84 RAB9A (0.58) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL29361694 0.84 RAB9A (0.58) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL14160771 0.79 NPC1 (0.43) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL4390043 0.79 PIK3CG (0.66) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL29236840 0.77 NPC1 (0.59) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL15157800 0.76 NPC1 (0.58) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL615340 0.76 SMN1; SMN2 (0.58) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL1562323 0.76 ESR1 (0.58) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL3062851 0.76 PIK3CG (0.61) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL2538594 0.76 KDM4E (0.59) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611224-A1 COMPOSITION, COMPOSITE FILM AND MEMBRANE ELECTRODE ASSEMBLY ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-02-19 EP disclosed
EP-2899034-B1 ORIGINAL PLANOGRAPHIC PRINTING PLATE, AND PLATE MAKING METHOD FUJIFILM CORP (JP) 2019-07-03 EP disclosed
EP-2906640-B1 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, METHODS FOR MAKING AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC DESOTO INT INC (US) 2017-11-15 EP disclosed
EP-2756043-B1 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC DESOTO INT INC (US) 2017-04-12 EP disclosed
US-9181628-B2 Coating/sealant systems, aqueous resinous dispersions, and methods of electrocoating PRC-DESOTO INTERNATIONAL, INC. (US) 2015-11-10 US disclosed
EP-2906640-A1 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, METHODS FOR MAKING AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC-Desoto International, Inc. (US) 2015-08-19 EP disclosed
EP-2899034-A1 ORIGINAL PLANOGRAPHIC PRINTING PLATE, AND PLATE MAKING METHOD FUJIFILM Corporation (JP) 2015-07-29 EP disclosed
CN-104797663-A Coating/sealant system, aqueous resinous dispersion, method of making aqueous resinous dispersion, and electrocoating process PRC DESOTO INT INC 2015-07-22 CN disclosed
US-20150192852-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD FUJIFILM CORPORATION (JP) 2015-07-09 US disclosed
US-9029437-B2 Coating/sealant systems, aqueous resinous dispersions, methods for making aqueous resinous dispersions, and methods of electrocoating PRC-DESOTO INTERNATIONAL, INC. (US) 2015-05-12 US disclosed
EP-2756043-A2 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC-Desoto International, Inc. (US) 2014-07-23 EP disclosed
CN-103814092-A Coating/sealant systems, aqueous resinous dispersions, and methods of electrocoating PRC DESOTO INT INC 2014-05-21 CN disclosed
WO-2013052190-A2 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC-DESOTO INTERNATIONAL, INC. (US) 2013-04-11 WO disclosed
US-20130065985-A1 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, METHODS FOR MAKING AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC-DESOTO INTERNATIONAL, INC. (US) 2013-03-14 US disclosed
US-20130065057-A1 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC-DESOTO INTERNATIONAL, INC. (US) 2013-03-14 US disclosed
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
EP-0129506-A2 Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids CIBA-GEIGY AG (CH) 1984-12-27 EP disclosed