SCHEMBL9306070

SCHEMBL9306070

O=C(O)CC(Cc1ccc(C(=O)O)cc1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CPA1 P15085 4/20 0.70
CPA3 P15088 2/20 0.70
CPB1 P15086 1/20 0.70
CPB2 Q96IY4 1/20 0.70
FOLH1 Q04609 6/20 0.66
CYP1A2 P05177 1/20 0.52
ANPEP P15144 1/20 0.50
ENPEP Q07075 1/20 0.50
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
MMP12 P39900 1/20 0.49
KMO O15229 1/20 0.48
MME P08473 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17537907 0.90 CPA1 (0.84) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL20560513 0.84 CPA1 (0.74) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL3205288 0.83 CPA1 (0.72) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL393002 0.82 CPA1 (1.00) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL1915564 0.82 CPA1 (1.00) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL5688996 0.82 CPA1 (1.00) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL2533621 0.81 CPA1 (0.70) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL17693395 0.81 CPA1 (0.70) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL11586603 0.81 CPA1 (0.70) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL28074267 0.81 CPA1 (0.70) CPA1CPA3CPB1CPB2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed