SCHEMBL3205288

SCHEMBL3205288

O=C(O)CC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CPA1 P15085 4/20 0.72
CPA3 P15088 3/20 0.72
CPB1 P15086 1/20 0.72
CPB2 Q96IY4 1/20 0.72
SLC7A5 Q01650 1/20 0.56
FOLH1 Q04609 1/20 0.54
CYP1A2 P05177 1/20 0.53
CA2 P00918 1/20 0.50
CAMK2A Q9UQM7 1/20 0.50
MME P08473 2/20 0.49
LTA4H P09960 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17537907 0.92 CPA1 (0.84) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL10436391 0.88 CYP1A2 (0.68) CPA1CPA3CPB1CPB2SLC7A5
SCHEMBL12528500 0.84 SLC7A5 (0.60) CPA1CPA3CPB1CPB2SLC7A5
SCHEMBL393002 0.84 CPA1 (1.00) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL1915564 0.84 CPA1 (1.00) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL5688996 0.84 CPA1 (1.00) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL12494638 0.84 SLC7A5 (0.60) CPA1CPA3CPB1CPB2SLC7A5
SCHEMBL9306070 0.83 CPA1 (0.70) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL2533621 0.83 CPA1 (0.70) CPA1CPA3CPB1CPB2FOLH1
SCHEMBL17693395 0.83 CPA1 (0.70) CPA1CPA3CPB1CPB2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11491117-B2 Compounds for the prevention and treatment of glucose intolerance related conditions and obesity Sorbonne Université (FR) 2022-11-08 US claimed
US-20200253889-A1 COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOSE INTOLERANCE RELATED CONDITIONS AND OBESITY. Sorbonne Université (FR) 2020-08-13 US claimed
EP-3691624-A1 COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOSE INTOLERANCE RELATED CONDITIONS AND OBESITY. Sorbonne Université (FR) 2020-08-12 EP claimed
CN-111386106-A Compounds for the prevention and treatment of disorders associated with glucose intolerance and obesity 索邦大学 2020-07-07 CN claimed
WO-2019068788-A1 COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOSE INTOLERANCE RELATED CONDITIONS AND OBESITY. Sorbonne Université (FR) 2019-04-11 WO claimed
EP-3466417-A1 COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOSE INTOLERANCE RELATED CONDITIONS AND OBESITY Sorbonne Université (FR) 2019-04-10 EP claimed
US-11491117-B2 Compounds for the prevention and treatment of glucose intolerance related conditions and obesity Sorbonne Université (FR) 2022-11-08 US disclosed
US-20200253889-A1 COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOSE INTOLERANCE RELATED CONDITIONS AND OBESITY. Sorbonne Université (FR) 2020-08-13 US disclosed
CN-111386106-A Compounds for the prevention and treatment of disorders associated with glucose intolerance and obesity 索邦大学 2020-07-07 CN disclosed
EP-3466417-A1 COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOSE INTOLERANCE RELATED CONDITIONS AND OBESITY Sorbonne Université (FR) 2019-04-10 EP disclosed
US-20100035309-A1 ANALYSIS AND ENHANCEMENT OF METABOLIC PATHWAYS FOR METHANOGENESIS LUCA TECHNOLOGIES, INC. (US) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11491117-B2 Compounds for the prevention and treatment of glucose intolerance related conditions and obesity GPR119, GYS2, PYGL CPA1 2063/4885CPA3 2325/4885CPB1 1272/4885
US-20200253889-A1 COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOSE INTOLERANCE RELATED CONDITIONS AND OBESITY. GPR119, CPT1A, GYS2 CPA1 1856/4885CPA3 2148/4885CPB1 1446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.