Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973137 | 0.84 | RAB9A (0.43) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL9306161 | 0.83 | MAPT (0.48) | MAPTRAB9ANPC1TAS1R3TAS1R1 | |
| SCHEMBL9306172 | 0.83 | MAPT (0.48) | MAPTRAB9ANPC1TAS1R3TAS1R1 | |
| SCHEMBL9305334 | 0.82 | RAB9A (0.42) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL10892199 | 0.82 | RAB9A (0.47) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL8972660 | 0.82 | SMN1; SMN2 (0.47) | MAPTRAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL9304858 | 0.81 | RAB9A (0.52) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL10893421 | 0.81 | RAB9A (0.49) | MAPTRAB9ANPC1TAS1R3TAS1R1 | |
| SCHEMBL10892259 | 0.79 | RAB9A (0.50) | MAPTRAB9ANPC1TAS1R3TAS1R1 | |
| SCHEMBL10892621 | 0.79 | SLC27A1 (0.48) | MAPTRAB9ANPC1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |