Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.70 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171425 | 0.93 | MTNR1A (0.79) | TSHRMTNR1AMTNR1BTP53PKM | |
| SCHEMBL29875454 | 0.93 | MTNR1A (0.79) | TSHRMTNR1AMTNR1BTP53PKM | |
| Acetic Acid SCHEMBL28264765 | 0.90 | MTNR1A (0.74) | TSHRMTNR1AMTNR1BTP53PKM | |
| SCHEMBL10811158 | 0.84 | MTNR1A (0.67) | TSHRMTNR1AMTNR1BTP53PKM | |
| SCHEMBL28010783 | 0.83 | MTNR1A (0.60) | TSHRMTNR1AMTNR1BTP53PKM | |
| SCHEMBL17084260 | 0.83 | TP53 (0.84) | TSHRTP53KMT2ARXFP1MEN1 | |
| SCHEMBL8326648 | 0.82 | KMT2A (0.60) | TSHRMTNR1AMTNR1BTP53PKM | |
| SCHEMBL18285439 | 0.82 | MTNR1A (0.63) | TSHRMTNR1AMTNR1BTP53PKM | |
| SCHEMBL4893387 | 0.81 | TP53 (0.87) | TSHRTP53KMT2ARXFP1MEN1 | |
| SCHEMBL31040569 | 0.81 | TP53 (0.87) | TSHRTP53KMT2ARXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280110-A | Fiber-reactive dye | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-18 | — | — | US | disclosed |