Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306381 | 0.82 | CBFB (0.59) | CBFBALDH1A1PDE5ATSHRSMN1; SMN2 | |
| SCHEMBL941420 | 0.81 | HPGD (0.54) | CBFBALDH1A1PDE5ASMN1; SMN2NPC1 | |
| SCHEMBL3967676 | 0.78 | NPC1 (0.46) | CBFBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL909787 | 0.77 | CBFB (0.54) | CBFBALDH1A1PDE5ATSHRSMN1; SMN2 | |
| SCHEMBL10432676 | 0.77 | CBFB (0.51) | CBFBALDH1A1PDE5ASMN1; SMN2KMT2A | |
| SCHEMBL23123180 | 0.74 | SMN1; SMN2 (0.54) | CBFBALDH1A1PDE5ASMN1; SMN2NPC1 | |
| SCHEMBL9306439 | 0.74 | DAO (0.46) | CBFBALDH1A1PDE5ASMN1; SMN2NPC1 | |
| SCHEMBL124264 | 0.74 | CBFB (1.00) | CBFBALDH1A1PDE5ASMN1; SMN2NPC1 | |
| SCHEMBL11205382 | 0.73 | NPC1 (0.39) | CBFBALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL125172 | 0.73 | CBFB (0.60) | CBFBALDH1A1PDE5ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |