Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941422 | 0.81 | KEAP1 (0.47) | DAOALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL9306376 | 0.81 | ALDH1A1 (0.43) | DAOALDH1A1SMN1; SMN2GUSBTLR8 | |
| SCHEMBL2735452 | 0.81 | TLR8 (0.46) | DAOALDH1A1SMN1; SMN2GUSBTLR8 | |
| SCHEMBL9306445 | 0.74 | CBFB (0.58) | ALDH1A1SMN1; SMN2CBFBGRK6NPC1 | |
| SCHEMBL7966170 | 0.73 | HSD17B10 (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2844595 | 0.72 | TP53 (0.43) | DAOALDH1A1SMN1; SMN2DRD4 | |
| SCHEMBL6139156 | 0.72 | PARP1 (0.41) | DAOALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL66296 | 0.71 | NOS1 (0.44) | DAOALDH1A1SMN1; SMN2GUSBNPC1 | |
| SCHEMBL4356909 | 0.71 | KDM4C (0.41) | ALDH1A1SMN1; SMN2TLR8L3MBTL1 | |
| SCHEMBL13040594 | 0.69 | NCF1 (0.50) | ALDH1A1GUSBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |