Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 2/20 | 0.59 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716477 | 0.83 | CBFB (0.54) | CBFBPDE5AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9306445 | 0.82 | CBFB (0.58) | CBFBPDE5AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL909787 | 0.78 | CBFB (0.54) | CBFBPDE5AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9828772 | 0.78 | PDE5A (0.51) | PDE5A | |
| SCHEMBL8047422 | 0.76 | KDM4E (0.44) | CBFBPDE5AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10835909 | 0.76 | DAO (0.38) | CBFBALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL23123180 | 0.75 | SMN1; SMN2 (0.54) | CBFBPDE5AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9306376 | 0.75 | ALDH1A1 (0.43) | CBFBPDE5AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL124264 | 0.75 | CBFB (1.00) | CBFBPDE5AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10432676 | 0.75 | CBFB (0.51) | CBFBPDE5AALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |