Iodide

Iodide

SCHEMBL9306494

CCCCCCCCCCCCOc1ccc(OCC(=O)NCCc2ccc[n+](CCC)c2)cc1C(C)(C)C.[I-]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
STAT3 P40763 1/20 0.39
HTT P42858 1/20 0.39
RAD52 P43351 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RCE1 Q9Y256 1/20 0.39
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
TSHR P16473 1/20 0.39
RECQL P46063 1/20 0.39
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL9308243 1.00 MTNR1A (0.41) MTNR1ASMN1; SMN2MEN1MAPTMAPK1
Iodide SCHEMBL9307839 0.94 MTNR1A (0.40) MTNR1ASMN1; SMN2THRATHRBTSHR
Iodide SCHEMBL9307104 0.94 MTNR1A (0.40) MTNR1ASMN1; SMN2THRATHRBTSHR
Iodide SCHEMBL9306267 0.91 TSHR (0.42) MTNR1ASMN1; SMN2THRATHRBTSHR
Iodide SCHEMBL9306675 0.91 TSHR (0.42) MTNR1ASMN1; SMN2THRATHRBTSHR
Iodide SCHEMBL9306731 0.91 CNR2 (0.41) MTNR1ATHRATHRBTSHRRECQL
Iodide SCHEMBL9305631 0.91 CNR2 (0.41) MTNR1ATHRATHRBTSHRRECQL
Iodide SCHEMBL9307316 0.88 SMN1; SMN2 (0.47) MTNR1ASMN1; SMN2MAPTKMT2ACNR2
Iodide SCHEMBL9307199 0.88 MTNR1A (0.42) MTNR1ASMN1; SMN2MAPTRAD52TSHR
Iodide SCHEMBL9306741 0.88 SMN1; SMN2 (0.47) MTNR1ASMN1; SMN2MAPTKMT2ACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5328921-A Antagonist of platelet activating factor AMERICAN CYANAMID COMPANY (US) 1994-07-12 US disclosed