Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.64 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.60 |
| ▸ | PAK4 | O96013 | 1/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.60 |
| ▸ | LTK | P29376 | 1/20 | 0.60 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
| ▸ | CDK8 | P49336 | 1/20 | 0.60 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.60 |
| ▸ | PRKX | P51817 | 1/20 | 0.60 |
| ▸ | NEK2 | P51955 | 1/20 | 0.60 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.60 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.60 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.60 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.60 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.60 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306624 | 0.88 | HPSE (0.52) | HPSECHEK1PRKD3PAK4PDGFRA | |
| SCHEMBL7248166 | 0.85 | CHEK1 (0.69) | CHEK1PRKD3PAK4PDGFRALTK | |
| SCHEMBL21018195 | 0.83 | CHEK1 (0.81) | CHEK1PRKD3PAK4PDGFRALTK | |
| SCHEMBL31612805 | 0.83 | HPSE (0.86) | HPSECHEK2NPC1ALDH1A1TP53 | |
| SCHEMBL21017799 | 0.80 | HPSE (0.66) | HPSECHEK2NPBWR1NPC1ALDH1A1 | |
| SCHEMBL21017817 | 0.80 | CHEK2 (0.79) | HPSEDGAT1KCNH2CHEK2NPC1 | |
| SCHEMBL7388571 | 0.79 | NPC1 (0.69) | HPSECHEK1PRKD3PAK4PDGFRA | |
| SCHEMBL7394696 | 0.79 | MEN1 (0.71) | CHEK1PRKD3PAK4PDGFRALTK | |
| SCHEMBL20982659 | 0.79 | NPC1 (0.85) | HPSECHEK2NPBWR1NPC1ALDH1A1 | |
| SCHEMBL18794741 | 0.79 | CHEK2 (0.65) | HPSECHEK2NPBWR1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5317078-A | Lower glass transition temperature and improved solvent solubility of polyether molding materials of macrocyclic monomers polymerized using an alkali basic catalyst and solvent; films | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1994-05-31 | — | — | US | disclosed |
| US-5245044-A | Di(hydroxyphenyl)-benzimidazole monomers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1993-09-14 | — | — | US | disclosed |