Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9306066 | 1.00 | ACHE (0.53) | ACHEDRD2DRD3PPARAABCB11 | |
| Oxalic Acid SCHEMBL9306052 | 1.00 | ACHE (0.53) | ACHEDRD2DRD3PPARAABCB11 | |
| SCHEMBL9306007 | 0.97 | ACHE (0.56) | ACHEDRD2DRD3PPARAABCB11 | |
| SCHEMBL9305104 | 0.97 | ACHE (0.56) | ACHEDRD2DRD3PPARAABCB11 | |
| SCHEMBL9304573 | 0.97 | ACHE (0.56) | ACHEDRD2DRD3PPARAABCB11 | |
| SCHEMBL9304578 | 0.84 | ACHE (0.60) | ACHEDRD2DRD3PPARACYP1A2 | |
| Oxalic Acid SCHEMBL9303696 | 0.80 | GRIN2B (0.48) | ACHEDRD2DRD3PPARAABCB11 | |
| SCHEMBL9514827 | 0.78 | GRIN2B (0.50) | ACHEDRD2DRD3PPARAABCB11 | |
| SCHEMBL9515221 | 0.78 | GRIN2B (0.50) | ACHEDRD2DRD3PPARAABCB11 | |
| SCHEMBL9304521 | 0.78 | GRIN2B (0.50) | ACHEDRD2DRD3PPARAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312961-A | 2-amino-7-hydroxytetralin carboxylalkyl ethers | ELF SANOFI (FR) | 1994-05-17 | — | — | US | disclosed |