Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304521 | 1.00 | GRIN2B (0.50) | GRIN2BDRD2DRD3HTR1DPPARG | |
| SCHEMBL9515221 | 1.00 | GRIN2B (0.50) | GRIN2BDRD2DRD3HTR1DPPARG | |
| Hydrochloric Acid SCHEMBL9305478 | 0.99 | GRIN2B (0.49) | GRIN2BDRD2DRD3HTR1DPPARG | |
| Hydrochloric Acid SCHEMBL9305469 | 0.99 | GRIN2B (0.49) | GRIN2BDRD2DRD3HTR1DPPARG | |
| Oxalic Acid SCHEMBL9303696 | 0.98 | GRIN2B (0.48) | GRIN2BDRD2DRD3HTR1DPPARG | |
| SCHEMBL8765893 | 0.94 | ADRB3 (0.46) | GRIN2BDRD2DRD3HTR1DPPARG | |
| SCHEMBL9305365 | 0.89 | GRIN2B (0.55) | GRIN2BDRD2DRD3HTR1DACHE | |
| SCHEMBL8765323 | 0.83 | MAPK1 (0.47) | GRIN2BDRD2DRD3HTR1DACHE | |
| SCHEMBL9443702 | 0.82 | ADRB3 (0.56) | GRIN2BDRD2DRD3HTR1D | |
| SCHEMBL9513685 | 0.82 | GRIN2B (0.51) | GRIN2BDRD2DRD3HTR1DACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383686-B1 | 2-AMINO-7-HYDROXYTETRALINE CARBOXYALKYL ETHERS | ELF SANOFI (FR) | 1993-08-04 | — | — | EP | disclosed |