Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343443 | 0.82 | CNR2 (0.78) | CNR2KDM4EMGAMHSD17B14HDAC8 | |
| SCHEMBL13475581 | 0.79 | CNR2 (0.64) | CNR2KDM4EMGAMHSD17B14HDAC8 | |
| SCHEMBL13475583 | 0.73 | CNR2 (0.55) | CNR2KDM4EMGAMHSD17B14HDAC8 | |
| SCHEMBL7832199 | 0.72 | CNR2 (1.00) | CNR2KDM4EMGAMHSD17B14HDAC8 | |
| SCHEMBL9755314 | 0.72 | MGAM (0.63) | CNR2KDM4EMGAMHDAC8MAPT | |
| SCHEMBL30227109 | 0.72 | CNR2 (1.00) | CNR2KDM4EMGAMHSD17B14HDAC8 | |
| SCHEMBL13475582 | 0.71 | KDM4E (1.00) | CNR2KDM4EMGAMHSD17B14HDAC8 | |
| SCHEMBL13475587 | 0.71 | CNR2 (0.72) | CNR2KDM4EMGAMHSD17B14HDAC8 | |
| SCHEMBL27838449 | 0.70 | CNR2 (0.96) | CNR2KDM4EMGAMHSD17B14HDAC8 | |
| SCHEMBL69325 | 0.70 | CES2 (0.43) | MAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292737-A | Inhibit protein kinase activity; antiinflammatory/antitumor agents; treatment for cardiovascular disorders | SPHINX PHARMACEUTICALS CORPORATION (US) | 1994-03-08 | — | — | US | disclosed |