SCHEMBL9306800

SCHEMBL9306800

FC(F)(F)c1cc(N(CC2CO2)CC2CO2)cc(N(CC2CO2)CC2CO2)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10967930 0.96 IDO1 (0.32) LMNA
SCHEMBL10966959 0.85 CETP (0.43) LMNA
SCHEMBL27781377 0.79 BACE1 (0.37) ARLMNA
SCHEMBL156988 0.77 LMNA (0.45) LMNA
SCHEMBL17480430 0.77 LMNA (0.45) LMNA
SCHEMBL26129056 0.75 POLB (0.38) ARLMNA
SCHEMBL14354443 0.74 LTA4H (0.40) LMNA
SCHEMBL6231100 0.72 ESR1 (0.37) LMNA
SCHEMBL9306822 0.72 AR (0.36) ARLMNA
SCHEMBL132721 0.72 MEN1 (0.43) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5283270-A Glycidyl diamines containing aromatic trifluoromethyl group and epoxy resins prepared therefrom OCCIDENTAL CHEMICAL CORPORATION (US) 1994-02-01 US disclosed