Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587682 | 0.98 | TAAR1 (0.42) | TAAR1TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8168961 | 0.92 | ALDH1A1 (0.40) | TAAR1TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6650386 | 0.89 | TAAR1 (0.40) | TAAR1TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3995603 | 0.81 | TAAR1 (0.43) | TAAR1TSHRALDH1A1CYP2A6L3MBTL1 | |
| SCHEMBL22613508 | 0.79 | ALDH1A1 (0.45) | TSHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL10627557 | 0.79 | CYP2A6 (0.41) | TAAR1TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2082178 | 0.77 | LMNA (0.42) | TSHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL1934134 | 0.77 | TSHR (0.36) | TSHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL1932565 | 0.76 | TSHR (0.38) | TSHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2084415 | 0.76 | LMNA (0.54) | TSHRALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336686-A | Glucocorticoid, progesterone and androgen antagonists; hormone inhibitors; antiproliferative activity; antitumor and carcinogenic agents | ROUSSEL-UCLAF (FR) | 1994-08-09 | — | — | US | disclosed |