Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425157 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL21412215 | 0.66 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL21412218 | 0.66 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL1811401 | 0.65 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL1811402 | 0.65 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL2999710 | 0.58 | TSHR (0.31) | — | |
| SCHEMBL9564568 | 0.55 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL5243332 | 0.54 | SMN1; SMN2 (0.43) | ALDH1A1 | |
| SCHEMBL11446909 | 0.53 | LMNA (0.39) | — | |
| SCHEMBL17865612 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360812-A | Fused 1,2,5-oxadiazole-2-oxides and their use | CASSELLA AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |
| EP-0574726-A1 | Annelated 1,2,5-oxadiozole-2 oxides and their use as pharmacological agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-22 | — | — | EP | disclosed |