Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | C1R | P00736 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893566 | 0.85 | MTNR1A (0.39) | MTNR1AMTNR1BKMT2ADHODHESR1 | |
| SCHEMBL10892677 | 0.81 | MTNR1A (0.38) | MTNR1AMTNR1BKMT2ADHODHESR1 | |
| SCHEMBL9307174 | 0.81 | MTNR1A (0.38) | MTNR1AMTNR1BKMT2AC1RCDK9 | |
| SCHEMBL9307145 | 0.80 | MTNR1A (0.42) | MTNR1AMTNR1BKMT2AESR1MAPT | |
| SCHEMBL10891074 | 0.79 | MTNR1A (0.37) | MTNR1AMTNR1BKMT2AMAPTALDH1A1 | |
| SCHEMBL10890457 | 0.79 | MTNR1A (0.40) | MTNR1AMTNR1BKMT2AMAPT | |
| SCHEMBL8972322 | 0.79 | RAB9A (0.43) | KMT2AMAPTHDAC3HDAC4HDAC1 | |
| Ammonia Solution, Strong SCHEMBL10865667 | 0.78 | RAB9A (0.42) | KMT2AMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL9307166 | 0.77 | MTNR1A (0.34) | MTNR1AMTNR1BKMT2AC1R | |
| Methylamine SCHEMBL10867850 | 0.76 | RAB9A (0.42) | KMT2AMAPTHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |