SCHEMBL9307207

SCHEMBL9307207

Cc1c(C)c(C)c2sc(C(CC(=O)O)C(O)=S)nc2c1C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSA P10619 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9307195 0.88
SCHEMBL9307865 0.72 NPC1 (0.39) CTSA
SCHEMBL9304179 0.70 GAA (0.41) CTSAL3MBTL1
SCHEMBL9305757 0.70 CTSA (0.35) CTSAL3MBTL1
SCHEMBL8972468 0.70 CTSA (0.35) CTSA
SCHEMBL9305741 0.70 STING1 (0.30)
SCHEMBL8972091 0.70 POLB (0.35) CTSA
SCHEMBL9304469 0.70 L3MBTL1 (0.31) L3MBTL1
SCHEMBL9307437 0.70 L3MBTL1 (0.31) L3MBTL1
SCHEMBL9305758 0.69 PKM (0.34) CTSAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
EP-0375614-B1 CORROSION-INHIBITING COATING COMPOSITIONS CIBA-GEIGY AG (CH) 1993-03-31 EP disclosed
US-5198482-A Benzothiazole carboxylic acid amine salt CIBA-GEIGY CORPORATION (US) 1993-03-30 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
EP-0375614-A1 Corrosion-inhibiting coating compositions CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed
US-4612049-A BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed