Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2674833 | 0.74 | ALDH1A1 (0.41) | KDM4ESMN1; SMN2ALDH1A1GLAGAA | |
| SCHEMBL8100877 | 0.73 | SMN1; SMN2 (0.56) | KDM4ESMN1; SMN2ALDH1A1GLAGAA | |
| SCHEMBL203981 | 0.72 | KDM4E (0.41) | KDM4ESMN1; SMN2ALDH1A1GLAGAA | |
| SCHEMBL2427657 | 0.71 | KDM4E (1.00) | KDM4ESMN1; SMN2ALDH1A1GLAGAA | |
| SCHEMBL9306694 | 0.71 | SMN1; SMN2 (0.53) | KDM4ESMN1; SMN2ALDH1A1GLAGAA | |
| SCHEMBL25311041 | 0.70 | PDE4A (0.42) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30228536 | 0.70 | KDM4E (0.96) | KDM4ESMN1; SMN2ALDH1A1GLAGAA | |
| SCHEMBL203984 | 0.70 | TLR7 (0.46) | POLBLMNA | |
| SCHEMBL11385268 | 0.70 | SMN1; SMN2 (0.52) | KDM4ESMN1; SMN2ALDH1A1GLAGAA | |
| SCHEMBL31649679 | 0.68 | KDM4E (0.63) | KDM4ESMN1; SMN2ALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340808-A | Fused pyridazinoquinazolone derivatives as neurotrophic agents | WARNER LAMBERT COMPANY (US) | 1994-08-23 | — | — | US | disclosed |
| US-4250177-A | ANTIALLERGENS | WARNER-LAMBERT COMPANY (US) | 1981-02-10 | — | — | US | disclosed |