Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 3/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025350 | 0.91 | PLK1 (0.49) | GAAPLK1KDM6BKDM4CBCL2L1 | |
| SCHEMBL9309430 | 0.80 | KDM4C (0.43) | GAAPLK1KDM4CBCL2L1MCL1 | |
| SCHEMBL11367974 | 0.79 | PLK1 (0.51) | GAAPLK1KDM6BKDM4CBCL2L1 | |
| SCHEMBL11523096 | 0.79 | ALDH1A1 (0.42) | GAAKDM4CBCL2L1MCL1HCAR3 | |
| SCHEMBL11145039 | 0.78 | PLK1 (0.47) | PLK1KDM6BKDM4CBCL2L1MCL1 | |
| SCHEMBL1894574 | 0.77 | LMNA (0.49) | PLK1KDM6BKDM4CBCL2L1MCL1 | |
| SCHEMBL524509 | 0.77 | MCL1 (0.39) | PLK1KDM4CBCL2L1MCL1PPARA | |
| SCHEMBL11175232 | 0.77 | PLK1 (0.46) | PLK1KDM6BKDM4CBCL2L1MCL1 | |
| SCHEMBL28412187 | 0.77 | PLK1 (0.55) | PLK1KDM6BKDM4CBCL2L1MCL1 | |
| SCHEMBL29033262 | 0.76 | PLK1 (0.42) | GAAPLK1KDM6BKDM4CBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352677-A | Antihyperlipidemic agents | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0407200-B1 | Cinnamamide derivatives | KANEGAFUCHI CHEMICAL IND (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5294624-A | Antiartheriosclerosis | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-15 | — | — | US | disclosed |
| US-5294643-A | Cinnamamide derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0407200-A1 | Cinnamamide derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-01-09 | — | — | EP | disclosed |