Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308163 | 0.84 | ALOX5 (0.42) | FFAR1ALOX5MEN1NPC1GAA | |
| SCHEMBL9208096 | 0.78 | ALOX5 (0.48) | ALOX5NPY1R | |
| SCHEMBL25525962 | 0.75 | TAAR1 (0.50) | MEN1KMT2AGRIN2B | |
| SCHEMBL1135279 | 0.75 | FYN (0.56) | FFAR1MAPK1FYN | |
| SCHEMBL9218794 | 0.73 | ALOX5 (0.65) | ALOX5 | |
| SCHEMBL25517325 | 0.72 | CYP4F2 (0.58) | FFAR1ALOX5MEN1GAAMAPT | |
| SCHEMBL5343612 | 0.72 | MEN1 (0.50) | MEN1MAPTKMT2AGRIN2B | |
| SCHEMBL8406860 | 0.71 | OPRL1 (0.51) | GRIN2B | |
| SCHEMBL9224261 | 0.70 | NPY1R (0.39) | ALOX5MEN1KMT2ANPY1R | |
| SCHEMBL21116575 | 0.70 | IDO1 (0.50) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994005281-A1 | PHENYLMETHYL DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |