Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228211 | 0.82 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9211596 | 0.82 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9208096 | 0.80 | ALOX5 (0.48) | NPY1RALOX5OPRM1OPRD1OPRK1 | |
| SCHEMBL9279813 | 0.75 | ALOX5 (0.41) | NPY1RALOX5SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9218794 | 0.75 | ALOX5 (0.65) | ALOX5 | |
| SCHEMBL13959797 | 0.73 | NPY1R (0.46) | NPY1RALOX5OPRD1 | |
| SCHEMBL9124520 | 0.73 | SLC6A4 (0.47) | NPY1RALOX5SLC6A2SLC6A4SLC22A1 | |
| SCHEMBL9307600 | 0.70 | FFAR1 (0.42) | NPY1RALOX5MEN1KMT2A | |
| SCHEMBL9223149 | 0.70 | OPRM1 (0.41) | SLC6A2SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL3151476 | 0.70 | SMN1; SMN2 (0.43) | NPY1RALOX5SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403859-A | PHENYLENE-CYCLIC ETHER COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-04-04 | — | — | US | disclosed |
| EP-0375404-B1 | Heterocyclic derivatives | ICI PLC (GB) | 1994-02-09 | — | — | EP | disclosed |
| US-5234950-A | Antiallergens, antiinflammatory agents; cardiovascular disorders, antiarthritic | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-10 | — | — | US | disclosed |
| US-5098930-A | Inhibitors of lipoxygenase for treatment of diseases mediated with leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-24 | — | — | US | disclosed |
| EP-0375404-A2 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-27 | — | — | EP | disclosed |