Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20928551 | 0.85 | ALOX15 (0.44) | PDE2AALOX15LMNATRPA1CHRM1 | |
| SCHEMBL3083574 | 0.84 | ALOX15 (0.45) | PDE2AALOX15LMNAGABRA1GABRB1 | |
| SCHEMBL4912678 | 0.81 | LMNA (0.59) | ALOX15LMNATRPA1CHRM1SLC6A2 | |
| SCHEMBL16423207 | 0.80 | PDE2A (0.41) | PDE2AALOX15LMNATRPA1CHRM1 | |
| SCHEMBL2429235 | 0.80 | PDE2A (0.58) | PDE2ALMNAAPLNRKDM4ENFKB1 | |
| SCHEMBL24838388 | 0.78 | ALOX15 (0.41) | PDE2AALOX15LMNATRPA1CHRM1 | |
| SCHEMBL15332748 | 0.76 | PDE2A (0.44) | PDE2ALMNAGABRA1GABRB1APLNR | |
| SCHEMBL4917683 | 0.74 | TSHR (0.57) | ALOX15LMNATRPA1CHRM1SLC6A2 | |
| SCHEMBL27675053 | 0.74 | HPGD (0.42) | ALOX15LMNATRPA1CHRM1SLC6A2 | |
| SCHEMBL3473581 | 0.72 | PDE2A (0.38) | PDE2AALOX15LMNATRPA1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342972-A | Rearranging phenol ester by fries shift, reduction, cyclization | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |
| US-5229530-A | 2,2-dialkyl-2,3-dihydro-6-bromobenzofuran | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-20 | — | — | US | disclosed |
| US-5200532-A | Dehydration, cyclization; acidic ion exchange resin and inorganic dessicant | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-06 | — | — | US | disclosed |
| EP-0474016-A2 | Method for the preparation of 2,3-dihydro-benzofuranes | BASF Aktiengesellschaft (DE) | 1992-03-11 | — | — | EP | disclosed |