SCHEMBL9307669

SCHEMBL9307669

Sc1cc2[nH]nnc2cc1Cl

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 1/20 0.37
CDK1 P06493 1/20 0.37
PIM1 P11309 1/20 0.37
DYRK1A Q13627 1/20 0.37
PIM3 Q86V86 1/20 0.37
CLK4 Q9HAZ1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL205009 0.83 MAPK13 (0.48) MAPK13CDK1PIM1DYRK1APIM3
SCHEMBL1021150 0.78 GRIN2D (0.44) MAPK13CDK1PIM1DYRK1APIM3
SCHEMBL8568181 0.76 MAPT (0.52) MAPK13CDK1PIM1DYRK1APIM3
SCHEMBL2705071 0.73
SCHEMBL30036958 0.72 GRIN2D (0.47) MAPK13CDK1PIM1DYRK1APIM3
SCHEMBL202829 0.72 GRIN2D (0.47) MAPK13CDK1PIM1DYRK1APIM3
SCHEMBL28695956 0.72 MAPT (0.43) MAPK13CDK1PIM1DYRK1APIM3
SCHEMBL10623115 0.69 PGK1 (0.43)
SCHEMBL22732815 0.69
SCHEMBL271074 0.67 FABP6 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5374639-A Plant fungicides CIBA-GEIGY CORPORATION (US) 1994-12-20 US disclosed
EP-0549532-A1 Benzotriazole-sulfonic acid derivatives and their use as microbicides CIBA-GEIGY AG (CH) 1993-06-30 EP disclosed