Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2102900 | 0.87 | ALDH1A1 (0.35) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL2599668 | 0.83 | ALDH1A1 (0.33) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL3062956 | 0.82 | ALDH1A1 (0.38) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL548963 | 0.80 | ALDH1A1 (0.36) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL11500450 | 0.74 | MEN1 (0.33) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL11211705 | 0.73 | ALDH1A1 (0.35) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL51201 | 0.71 | FFAR3 (0.41) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL10882829 | 0.70 | TET2 (0.30) | — | |
| SCHEMBL10875807 | 0.69 | MEN1 (0.31) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| Carbon Tetrachloride SCHEMBL10421671 | 0.69 | ALDH1A1 (0.42) | MEN1ALDH1A1CYP1A2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322948-A | Reacting unsaturated diacid or derivative with hydroxylamine or a salt thereof to form N-hydroxy-2-aminobutane diacid derivative | HOECHST CELANESE CORPORATION (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0511446-A2 | Process for preparing pyridinecarboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1992-11-04 | — | — | EP | disclosed |
| EP-0456504-A2 | Process for preparing pyridinecarboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1991-11-13 | — | — | EP | disclosed |
| US-5047542-A | Reaction of ketoester with unsaturated aldehyde or ketone | HOECHST CELANESE CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0415767-A2 | Process for preparing pyridine carboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4871859-A | REACTING KETOESTER WITH UNSATURATED ALDEHYDE OR KETONE AND AMMONIUM SALT IN SOLVENT AND DEHYDROGENATION CATALYST | HOECHST CELANESE CORPORATION | 1989-10-03 | — | — | US | disclosed |
| WO-1989008103-A1 | PROCESS FOR PREPARING PYRIDINE CARBOXYLIC ACID ESTERS | HOECHST CELANESE CORPORATION (US) | 1989-09-08 | — | — | WO | disclosed |