Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18387787 | 0.84 | TSHR (0.52) | LOXL2TSHRIDO1ALDH1A1KCNJ1 | |
| SCHEMBL776520 | 0.81 | LOXL2 (0.57) | LOXL2TSHRIDO1ALDH1A1KCNJ1 | |
| SCHEMBL75530 | 0.81 | LOXL2 (0.55) | LOXL2TSHRIDO1ALDH1A1KCNJ1 | |
| SCHEMBL7107843 | 0.78 | LOXL2 (0.52) | LOXL2TSHRIDO1ALDH1A1KCNJ1 | |
| SCHEMBL1627332 | 0.78 | TSHR (0.53) | LOXL2TSHRIDO1ALDH1A1ACHE | |
| SCHEMBL97944 | 0.78 | LOXL2 (0.52) | LOXL2TSHRIDO1ALDH1A1KCNJ1 | |
| SCHEMBL18387801 | 0.76 | LOXL2 (0.50) | LOXL2TSHRIDO1ALDH1A1KCNJ1 | |
| SCHEMBL7107845 | 0.76 | LOXL2 (0.50) | LOXL2TSHRIDO1ALDH1A1KCNJ1 | |
| SCHEMBL27597568 | 0.76 | LOXL2 (0.50) | LOXL2TSHRIDO1ALDH1A1KCNJ1 | |
| SCHEMBL9308189 | 0.76 | LOXL2 (0.50) | LOXL2TSHRIDO1ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417870-B1 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | DIAGNOSTIKFORSCHUNG INST (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5302370-A | Form complexes with rhenium and technetium | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1994-04-12 | — | — | US | disclosed |
| EP-0502594-A1 | Chelates, their metal complexes as well as their use in diagnosis and therapy | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1992-09-09 | — | — | EP | disclosed |
| EP-0417870-A2 | Chelates for complexation of radioactive isotopes, their metal complexes and their use in diagnosis and therapy | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1991-03-20 | — | — | EP | disclosed |