Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75530 | 0.82 | LOXL2 (0.55) | LOXL2TSHRCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL776520 | 0.79 | LOXL2 (0.57) | LOXL2TSHRCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL97944 | 0.79 | LOXL2 (0.52) | LOXL2TSHRCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL1627332 | 0.79 | TSHR (0.53) | LOXL2TSHRCYP2C19IDO1ALDH1A1 | |
| SCHEMBL7107843 | 0.79 | LOXL2 (0.52) | LOXL2TSHRCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL18387787 | 0.78 | TSHR (0.52) | LOXL2TSHRCYP2C19CYP1A2IDO1 | |
| SCHEMBL18387801 | 0.78 | LOXL2 (0.50) | LOXL2TSHRCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL9307922 | 0.76 | LOXL2 (0.58) | LOXL2TSHRCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL9155804 | 0.76 | LOXL2 (0.48) | LOXL2TSHRCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL6667989 | 0.75 | TSHR (0.49) | LOXL2TSHRCYP2C19CYP1A2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044965-B1 | PROCESS FOR THE PREPARATION OF AROMATIC SULFUR COMPOUNDS | NIPPON FINECHEMICAL CO LTD (JP) | 2003-10-01 | — | — | EP | disclosed |
| US-6376716-B1 | REACTING AN AROMATIC THIOETHER WITH LEWIS ACIDS; FORMING AROMATIC MERCAPTAN | NIPPON FINECHEMICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1044965-A1 | PROCESS FOR THE PREPARATION OF AROMATIC SULFUR COMPOUNDS | Nippon Finechemical Co., Ltd. (JP) | 2000-10-18 | — | — | EP | disclosed |