Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309115 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL9310196 | 0.90 | ALDH1A1 (0.53) | ALDH1A1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL9027990 | 0.90 | ALDH1A1 (0.53) | ALDH1A1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL9308618 | 0.87 | KDM4E (0.53) | ALDH1A1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL9028587 | 0.83 | KDM4E (0.49) | ALDH1A1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL9310714 | 0.77 | HPGD (0.62) | ALDH1A1HTTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9028887 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL9034399 | 0.71 | HPGD (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL9308729 | 0.71 | HPGD (0.58) | ALDH1A1HTTKDM4EMEN1KMT2A | |
| SCHEMBL9309615 | 0.70 | HPGD (0.51) | ALDH1A1SMN1; SMN2HSD17B10CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | claimed |
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |