Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028887 | 0.90 | ALDH1A1 (0.46) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9307946 | 0.83 | ALDH1A1 (0.49) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9309115 | 0.83 | ALDH1A1 (0.49) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9308618 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9310196 | 0.72 | ALDH1A1 (0.53) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9027990 | 0.72 | ALDH1A1 (0.53) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9028232 | 0.68 | ALDH1A1 (0.44) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9310707 | 0.67 | HPGD (0.50) | ALDH1A1KMT2ASMN1; SMN2HSD17B10LMNA | |
| SCHEMBL9308729 | 0.65 | HPGD (0.58) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9034399 | 0.65 | HPGD (0.52) | ALDH1A1MEN1KMT2ASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486386-B1 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR (FR) | 1996-07-17 | — | — | EP | claimed |