Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310488 | 0.87 | CYP4F2 (0.38) | TSHRNPC1POLBALDH1A1HSD17B10 | |
| SCHEMBL9308585 | 0.80 | TBXAS1 (0.50) | TBXA2RTBXAS1MAP2K7CDC25ACDC25B | |
| Seratrodast SCHEMBL98402 | 0.79 | TBXAS1 (0.52) | TBXA2RTBXAS1MAP2K7CDC25ACDC25B | |
| SCHEMBL9308117 | 0.79 | TBXAS1 (0.52) | TBXA2RTBXAS1MAP2K7CDC25ACDC25B | |
| Seratrodast SCHEMBL98403 | 0.79 | TBXAS1 (0.52) | TBXA2RTBXAS1MAP2K7CDC25ACDC25B | |
| SCHEMBL4362398 | 0.76 | HPGD (0.54) | HPGDTSHRTBXA2RLTB4RPTGER1 | |
| SCHEMBL2490724 | 0.75 | TBXA2R (0.46) | TBXA2RPTGER1PTGFRPTGER2TBXAS1 | |
| SCHEMBL4370817 | 0.74 | HPGD (0.56) | HPGDTSHRTBXA2RLTB4RPTGER1 | |
| SCHEMBL4366864 | 0.74 | HPGD (0.56) | HPGDTSHRTBXA2RLTB4RPTGER1 | |
| SCHEMBL4369023 | 0.74 | HPGD (0.56) | HPGDTSHRTBXA2RLTB4RPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | disclosed |