Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307983 | 0.87 | HPGD (0.42) | ALDH1A1POLBTSHRNPC1HSD17B10 | |
| SCHEMBL9309892 | 0.76 | PTPN1 (0.44) | CYP4F2CYP4A11PTPN1SMN1; SMN2CYP3A4 | |
| SCHEMBL9311254 | 0.74 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1POLBTSHR | |
| SCHEMBL2515076 | 0.74 | NPC1 (0.42) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9310852 | 0.73 | PTPRC (0.43) | — | |
| SCHEMBL9019233 | 0.73 | PTPRC (0.43) | — | |
| SCHEMBL11830228 | 0.70 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1PTPN1TSHR | |
| SCHEMBL9664249 | 0.70 | MEN1 (0.44) | CYP4F2CYP4A11ALDH1A1PTPN1SMN1; SMN2 | |
| SCHEMBL11095339 | 0.69 | KMT2A (0.41) | CYP4F2CYP4A11ALDH1A1POLBL3MBTL1 | |
| SCHEMBL11095337 | 0.69 | KMT2A (0.41) | CYP4F2CYP4A11ALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61044840-A | — | — | None | — | — | JP | disclosed |
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | disclosed |