Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311108 | 0.99 | SIGMAR1 (0.36) | TBXA2RSIGMAR1CYP2C9HTR2AHRH1 | |
| SCHEMBL9310821 | 0.96 | HRH1 (0.37) | TBXA2RSIGMAR1CYP2C9HTR2AHRH1 | |
| SCHEMBL9310562 | 0.87 | MEN1 (0.42) | TBXA2RSIGMAR1CYP2C9HTR2AHRH1 | |
| SCHEMBL9310154 | 0.86 | TBXA2R (0.39) | TBXA2RSIGMAR1CYP2C9HTR2AHRH1 | |
| SCHEMBL9308785 | 0.86 | TBXA2R (0.39) | TBXA2RSIGMAR1CYP2C9HTR2AHRH1 | |
| SCHEMBL9307887 | 0.86 | TBXA2R (0.39) | TBXA2RSIGMAR1CYP2C9HTR2AHRH1 | |
| SCHEMBL10866141 | 0.86 | SIGMAR1 (0.41) | TBXA2RSIGMAR1CYP2C9HTR2AHRH1 | |
| SCHEMBL9662366 | 0.84 | SIGMAR1 (0.38) | TBXA2RSIGMAR1CYP2C9HTR2AHRH1 | |
| SCHEMBL9310772 | 0.83 | HTR2A (0.36) | TBXA2RSIGMAR1CYP2C9HTR2AHRH1 | |
| SCHEMBL9308388 | 0.83 | TBXA2R (0.56) | TBXA2RCYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | disclosed |