SCHEMBL9308174

SCHEMBL9308174

O=P(O)(O)Oc1ccccc1-c1cccc(-c2ccccc2OP(=O)(O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 10/20 0.55
INPP5A Q14642 5/20 0.55
INPP5B P32019 2/20 0.55
PTPN5 P54829 2/20 0.50
SRC P12931 3/20 0.49
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
PDE3A Q14432 1/20 0.49
HSD17B10 Q99714 1/20 0.49
AKT1 P31749 1/20 0.44
GPR84 Q9NQS5 1/20 0.44
PTGER1 P34995 2/20 0.41
PTGER4 P35408 2/20 0.41
PTGER3 P43115 2/20 0.41
PTGER2 P43116 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9308423 0.90 INPPL1 (0.49) INPPL1INPP5AINPP5BPTPN5SRC
SCHEMBL3693358 0.89 KDM4E (0.56) INPPL1INPP5AINPP5BPTPN5SRC
Hydrochloric Acid SCHEMBL28439740 0.87 KDM4E (0.55) INPPL1INPP5AINPP5BPTPN5SRC
SCHEMBL31530595 0.86 PTGER1 (0.54) INPPL1INPP5AINPP5BPTPN5KDM4E
SCHEMBL28781329 0.85 PTPN5 (0.50) INPPL1INPP5AINPP5BPTPN5SRC
SCHEMBL9645945 0.84 INPPL1 (0.61) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL27780600 0.81 ALDH1A1 (0.53) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL4451434 0.79 INPPL1 (0.52) INPPL1INPP5AINPP5BPTPN5SRC
SCHEMBL343312 0.79 INPPL1 (0.47) INPPL1INPP5AINPP5BPTPN5SRC
SCHEMBL29604346 0.79 INPPL1 (0.52) INPPL1INPP5AINPP5BPTPN5SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3293191-B1 PHOSPHITES WITH A DIHYDROXYTERPHENYL EVONIK DEGUSSA GMBH (DE) 2018-11-14 EP disclosed
EP-3293192-B1 PHOSPHITES WITH A DIHYDROXYTERPHENYL WITH A TETRAPHENYL DIOXAPHOSPHOLANE EVONIK DEGUSSA GMBH (DE) 2018-11-14 EP disclosed
US-5278212-A Hydroxy phenyl organo phosphorus compound ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-01-11 US disclosed