SCHEMBL9308423

SCHEMBL9308423

O=P(O)(O)Oc1ccccc1-c1cccc(O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 4/20 0.49
INPP5B P32019 2/20 0.49
INPP5A Q14642 2/20 0.49
PTPN5 P54829 2/20 0.46
SRC P12931 2/20 0.44
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
PDE3A Q14432 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ADRA2A P08913 3/20 0.42
ADRA2B P18089 3/20 0.42
ADRA2C P18825 3/20 0.42
HSD17B1 P14061 2/20 0.42
HSD17B2 P37059 2/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
GAPDH P04406 1/20 0.40
GPR84 Q9NQS5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9308174 0.90 INPPL1 (0.55) INPPL1INPP5BINPP5APTPN5SRC
SCHEMBL9308419 0.89 PTPN5 (0.43) PTPN5SRCADRA2AADRA2BADRA2C
SCHEMBL9307758 0.88 INPPL1 (0.46) INPPL1INPP5BINPP5APTPN5SRC
SCHEMBL3693358 0.83 KDM4E (0.56) INPPL1INPP5BINPP5APTPN5SRC
SCHEMBL9309017 0.82 MAOA (0.45) INPPL1INPP5BINPP5AHSD17B1HSD17B2
Hydrochloric Acid SCHEMBL28439740 0.81 KDM4E (0.55) INPPL1INPP5BINPP5APTPN5SRC
SCHEMBL31530595 0.80 PTGER1 (0.54) INPPL1INPP5BINPP5APTPN5KDM4E
SCHEMBL9308571 0.79 INPPL1 (0.41) INPPL1INPP5BINPP5AHSD17B1HSD17B2
SCHEMBL28781329 0.79 PTPN5 (0.50) INPPL1INPP5BINPP5APTPN5SRC
SCHEMBL9645945 0.78 INPPL1 (0.61) INPPL1INPP5BINPP5ASRCKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5278212-A Hydroxy phenyl organo phosphorus compound ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-01-11 US disclosed