Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GYS1 | P13807 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310967 | 0.84 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL9307737 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL9309145 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL9309310 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL9307727 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL1446429 | 0.77 | MAPT (0.57) | MAPTALDH1A1KDM4ERAB9AL3MBTL1 | |
| SCHEMBL9308869 | 0.75 | ALDH1A1 (0.58) | ALDH1A1HPGDCA2TSHRL3MBTL1 | |
| SCHEMBL9309024 | 0.74 | MAPT (0.42) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL14894965 | 0.73 | SMN1; SMN2 (0.49) | MAPTALDH1A1CA2L3MBTL1FTO | |
| SCHEMBL14894966 | 0.73 | SMN1; SMN2 (0.49) | MAPTALDH1A1CA2L3MBTL1FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |