Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308216 | 0.84 | MAPT (0.44) | ALDH1A1MAPTPOLBKDM4EKMT2A | |
| SCHEMBL18556235 | 0.76 | MAPT (0.56) | ALDH1A1MAPTPOLBKDM4ERECQL | |
| SCHEMBL14904738 | 0.76 | MAPT (0.56) | ALDH1A1MAPTPOLBKDM4ERECQL | |
| SCHEMBL11697405 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBKDM4ERECQL | |
| SCHEMBL6331720 | 0.76 | ALDH1A1 (0.63) | ALDH1A1POLBKDM4EKMT2AHPGD | |
| SCHEMBL17929301 | 0.74 | CNR2 (0.42) | ALDH1A1MAPTKMT2AFKBP1A | |
| SCHEMBL13469117 | 0.72 | ALDH1A1 (0.54) | ALDH1A1POLBKDM4EKMT2AMEN1 | |
| SCHEMBL9310097 | 0.72 | MAPT (0.41) | ALDH1A1MAPTPOLBKDM4ERECQL | |
| SCHEMBL20366865 | 0.72 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2AMEN1FKBP1A | |
| SCHEMBL17929299 | 0.71 | FKBP1A (0.43) | ALDH1A1MAPTKMT2AFKBP1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |