Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308762 | 0.87 | ALDH1A1 (0.53) | MEN1KMT2AATMLMNAALDH1A1 | |
| SCHEMBL22251805 | 0.84 | ACE (0.44) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL9311330 | 0.84 | SLC6A4 (0.52) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL3310151 | 0.83 | ATM (0.56) | MEN1KMT2AKDM4EATMLMNA | |
| SCHEMBL3313145 | 0.82 | ALDH1A1 (0.57) | MEN1KMT2AKDM4EATMLMNA | |
| SCHEMBL8913587 | 0.80 | ATM (0.52) | MEN1KMT2AATMLMNAALDH1A1 | |
| SCHEMBL20676108 | 0.79 | MEN1 (0.56) | MEN1KMT2AKDM4EATMLMNA | |
| SCHEMBL22360604 | 0.78 | CYP2D6 (0.56) | MEN1KMT2AKDM4EATMLMNA | |
| SCHEMBL26334231 | 0.78 | ATM (0.56) | MEN1KMT2AKDM4EATMLMNA | |
| SCHEMBL9309862 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308848-A | Side effect reduction | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0452107-A1 | Pyrimidinedione derivatives and antiarrythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-16 | — | — | EP | disclosed |