Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3310151 | 0.93 | ATM (0.56) | ATMALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3313145 | 0.84 | ALDH1A1 (0.57) | ATMALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9308762 | 0.82 | ALDH1A1 (0.53) | ATMALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28523059 | 0.81 | KMT2A (0.56) | ATMALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL9308521 | 0.80 | MEN1 (0.58) | ATMALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL17892122 | 0.78 | ATM (0.55) | ATMALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7475308 | 0.77 | ALDH1A1 (0.70) | ALDH1A1MAPK1GAACYP2C19PKM | |
| SCHEMBL17892175 | 0.77 | IGF1R (0.54) | ATMALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4083554 | 0.76 | LMNA (0.60) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL9643788 | 0.76 | LMNA (0.60) | ALDH1A1LMNAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670508-A | ANTITUMOR AGENTS FOR BRAIN TUMORS | NATIONAL SCIENCE COUNCIL (TW) | 1997-09-23 | — | — | US | disclosed |