Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015805 | 0.87 | GRIN1 (0.40) | KIF11KMT2AALDH1A1GRIN1GRIN2A | |
| SCHEMBL4459760 | 0.86 | GRIN1 (0.31) | KIF11GRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL9308983 | 0.86 | GRIA4 (0.35) | NPC1ALDH1A1RAB9AL3MBTL1GRIN1 | |
| SCHEMBL4472117 | 0.84 | THRA (0.39) | LMNAALDH1A1TP53HTR2AHTR2C | |
| SCHEMBL11442348 | 0.83 | GRIN1 (0.34) | KIF11GRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL9842165 | 0.82 | GRIN1 (0.42) | ALDH1A1GRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL136467 | 0.80 | GRIN1 (0.44) | ALDH1A1GRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL11438838 | 0.79 | GRIN1 (0.36) | KIF11KMT2AGRIN1GRIN2AGRIN2D | |
| SCHEMBL11420664 | 0.78 | GRIN1 (0.40) | KIF11ALDH1A1GRIN1GRIN2AGRIN2D | |
| SCHEMBL5210805 | 0.75 | TSHR (0.37) | MEN1KMT2AMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2886566-B1 | Rubber composition and vehicle tyre | CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) | 2016-09-14 | — | — | EP | disclosed |
| EP-2886566-A1 | Rubber composition and vehicle tyre | Continental Reifen Deutschland GmbH (DE) | 2015-06-24 | — | — | EP | disclosed |
| US-5286457-A | Agitation to cause splashing and drop formation; reduce volatile monomer | THE DOW CHEMICAL COMPANY (US) | 1994-02-15 | — | — | US | disclosed |
| EP-0316857-B1 | Amine containing initiator system for anionic polymerization | DOW CHEMICAL CO (US) | 1993-12-29 | — | — | EP | disclosed |
| US-5120805-A | Agitation; reduce volatile monomer accumulation | THE DOW CHEMICAL COMPANY (US) | 1992-06-09 | — | — | US | disclosed |
| US-5112920-A | Amine containing monomers | THE DOW CHEMICAL COMPANY (US) | 1992-05-12 | — | — | US | disclosed |
| US-4960842-A | MULTIFUNCTIONAL LITHIUM INITIATOR | THE DOW CHEMICAL COMPANY (US) | 1990-10-02 | — | — | US | disclosed |
| WO-1989004843-A1 | AMINE CONTAINING INITIATOR SYSTEM FOR ANIONIC POLYMERIZATION | THE DOW CHEMICAL COMPANY (US) | 1989-06-01 | — | — | WO | disclosed |
| EP-0316857-A2 | Amine containing initiator system for anionic polymerization | THE DOW CHEMICAL COMPANY (US) | 1989-05-24 | — | — | EP | disclosed |
| US-4196154-A | Soluble multifunctional lithium containing initiator | THE DOW CHEMICAL COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4172100-A | 1,3-Bis[1-(4-methylphenyl)ethenyl]benzene | THE DOW CHEMICAL COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| US-4172190-A | Soluble multifunctional lithium containing initiator | THE DOW CHEMICAL COMPANY (US) | 1979-10-23 | — | — | US | disclosed |