Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | KIF11 | P52732 | 10/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210805 | 0.90 | TSHR (0.37) | TSHR | |
| SCHEMBL4015805 | 0.89 | GRIN1 (0.40) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL11442348 | 0.88 | GRIN1 (0.34) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL9308983 | 0.88 | GRIA4 (0.35) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL9308548 | 0.86 | KIF11 (0.35) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL9842165 | 0.83 | GRIN1 (0.42) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL136467 | 0.81 | GRIN1 (0.44) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL11438838 | 0.80 | GRIN1 (0.36) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL4472117 | 0.79 | THRA (0.39) | — | |
| SCHEMBL9135923 | 0.79 | KIF11 (0.30) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211272-B1 | BUTADIENE/ISOPRENE/AROMATIC VINYL HYDROCARBON SEVENBLOCK COPOLYMER AND THE PREPARING METHOD THEREOF | CHINA PETROCHEMICAL CORP (CN) | 2007-09-12 | — | — | EP | claimed |
| EP-1266916-B1 | MULTIBLOCK COPOLYMER AND THE PREPARING METHOD THEREOF | CHINA PETROLEUM & CHEMICAL (CN) | 2005-12-14 | — | — | EP | claimed |
| US-6777499-B2 | SYMMETRIC STRUCTURE Y-X-Y WHERE X IS A BLOCK OF BUTADIENE AND/OR ISOPRENE AND Y IS A BLOCK OF A RANDOM COPOLYMER OF CONJUGATED DIENE AND MONOVINYL AROMATIC POLYMER; USE AS TIRE TREAD RUBBER WITH VERY LOW ENERGY LOSS | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2004-08-17 | — | — | US | claimed |
| US-20030013826-A1 | Multiblock interpolymers and processes for the preparation thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2003-01-16 | — | — | US | claimed |
| EP-1266916-A1 | MULTIBLOCK COPOLYMER THE PREPARING METHOD THEREOF | China Petroleum & Chemical Corporation (CN) | 2002-12-18 | — | — | EP | claimed |
| EP-1211272-A1 | BUTADIENE/ISOPRENE/AROMATIC VINYL HYDROCARBON SEVENBLOCK COPOLYMER AND THE PREPARING METHOD THEREOF | China Petro-Chemical Corporation (CN) | 2002-06-05 | — | — | EP | claimed |
| US-6372853-B1 | IN THE PRESENCE OF DIFUNCTIONAL LITHIUM BASED INITIATORS, THEN CHARGING MIXTURES CONSISTING OF THE OTHER MONOMERS INTO THE RESULTING LIVING POLYMER; BLOCK POLYMERS; OLIGOMERIZATION | CHINA PETROCHEMICAL CORPORATION (CN) | 2002-04-16 | — | — | US | claimed |
| EP-0472749-A1 | Blanking process for reaction mixture | THE DOW CHEMICAL COMPANY (US) | 1992-03-04 | — | — | EP | claimed |
| US-5089572-A | Pretreatment with dilithium substituted symetrical aromatic hydrocarbons for removal of proton-donor impurities | THE DOW CHEMICAL COMPANY (US) | 1992-02-18 | — | — | US | claimed |
| US-9701809-B2 | Rubber mixture and vehicle tire | CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-20160297948-A1 | RUBBER MIXTURE AND VEHICLE TIRE | CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
| EP-2886566-B1 | Rubber composition and vehicle tyre | CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) | 2016-09-14 | — | — | EP | disclosed |
| US-20160168179-A1 | CYCLOPOLYARYLENE METAL COMPLEX | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2016-06-16 | — | — | US | disclosed |
| US-9266909-B2 | Cyclic compound containing functional group or containing no functional group, and method for producing same | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2016-02-23 | — | — | US | disclosed |
| EP-0316857-A2 | Amine containing initiator system for anionic polymerization | THE DOW CHEMICAL COMPANY (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0001977-B1 | SOLUBLE MULTIFUNCTIONAL LITHIUM CONTAINING INITIATORS AND THEIR USE IN A PROCESS FOR POLYMERISATION | THE DOW CHEMICAL COMPANY (US) | 1982-02-03 | — | — | EP | disclosed |
| US-4196154-A | Soluble multifunctional lithium containing initiator | THE DOW CHEMICAL COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4172100-A | 1,3-Bis[1-(4-methylphenyl)ethenyl]benzene | THE DOW CHEMICAL COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| US-4172190-A | Soluble multifunctional lithium containing initiator | THE DOW CHEMICAL COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| EP-0001977-A1 | Soluble multifunctional lithium containing initiators and their use in a process for polymerisation | THE DOW CHEMICAL COMPANY (US) | 1979-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168179-A1 | CYCLOPOLYARYLENE METAL COMPLEX | MCCC2, MT-CO3, SCO2 | GRIN1 3179/4885GRIN2A 3319/4885GRIN2D 2733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.