Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | HINT1 | P49773 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308744 | 1.00 | AHCY (0.32) | AHCYPDE10AHINT1CHRNB2CHRNA5 | |
| SCHEMBL9309879 | 0.86 | AHCY (0.39) | AHCYHINT1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL9309888 | 0.86 | AHCY (0.39) | AHCYHINT1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL9311355 | 0.81 | AHCY (0.42) | AHCYADORA2B | |
| SCHEMBL9311362 | 0.81 | AHCY (0.42) | AHCYADORA2B | |
| SCHEMBL9707227 | 0.81 | CHKA (0.36) | HINT1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL9309410 | 0.81 | CHKA (0.36) | HINT1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL9752270 | 0.73 | PDE2A (0.32) | — | |
| SCHEMBL9020083 | 0.69 | MGMT (0.41) | HINT1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL10515960 | 0.68 | AHCY (0.42) | AHCYHINT1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |