Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
| ▸ | HINT1 | P49773 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309888 | 1.00 | AHCY (0.39) | AHCYHINT1ADORA3ADORA2AADORA2B | |
| SCHEMBL9309410 | 0.88 | CHKA (0.36) | HINT1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL9707227 | 0.88 | CHKA (0.36) | HINT1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL9308749 | 0.86 | AHCY (0.32) | AHCYHINT1ADORA3ADORA2AADORA2B | |
| SCHEMBL9308744 | 0.86 | AHCY (0.32) | AHCYHINT1ADORA3ADORA2AADORA2B | |
| SCHEMBL9310964 | 0.77 | AHCY (0.53) | AHCYADORA2BGSK3ARPS6KA3MAPK14 | |
| SCHEMBL9310971 | 0.77 | AHCY (0.53) | AHCYADORA2BGSK3ARPS6KA3MAPK14 | |
| SCHEMBL10515960 | 0.76 | AHCY (0.42) | AHCYHINT1ADORA3ADORA2AADORA2B | |
| SCHEMBL9020083 | 0.76 | MGMT (0.41) | HINT1ADORA2AADORA2BCHRNB2CHRNA5 | |
| SCHEMBL9752163 | 0.75 | MGMT (0.39) | AHCYADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |