Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828751 | 0.87 | MEN1 (0.55) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8324505 | 0.87 | MAPT (0.66) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9410518 | 0.86 | MAPT (0.69) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8752439 | 0.86 | MEN1 (0.66) | MAPTGAAKMT2ALMNAMEN1 | |
| SCHEMBL18530341 | 0.85 | MAPT (0.64) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7894861 | 0.85 | MAPT (0.68) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11679320 | 0.84 | POLB (0.68) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1817688 | 0.84 | RAB9A (0.64) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24538415 | 0.83 | MAPT (0.75) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4003071 | 0.83 | MAPT (0.66) | MAPTHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118185381-A | Marek pen ink and preparation method thereof | 深圳千岸科技股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| US-5371226-A | Hypotensive agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-12-06 | — | — | US | disclosed |
| EP-0561252-A1 | 2-Oxoquinoline derivatives as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-09-22 | — | — | EP | disclosed |