SCHEMBL4003071

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29128669	0.88	MAPT (0.56)	MAPTMAPK1HDAC3HDAC4HDAC1
	SCHEMBL9410518	0.86	MAPT (0.69)	MAPTMAPK1HDAC3HDAC4HDAC1
	SCHEMBL7894861	0.85	MAPT (0.68)	MAPTMAPK1HDAC3HDAC4HDAC1
	SCHEMBL2636652	0.85	NPSR1 (0.61)	MAPTMAPK1HDAC3HDAC4HDAC1
	SCHEMBL11802189	0.84	ALDH1A1 (0.67)	MAPTMAPK1SMN1; SMN2NPSR1GAA
	SCHEMBL24538415	0.83	MAPT (0.75)	MAPTMAPK1HDAC3HDAC4HDAC1
	SCHEMBL9308750	0.83	MAPT (0.66)	MAPTMAPK1HDAC3HDAC4HDAC1
	SCHEMBL28041453	0.83	NPSR1 (0.59)	MAPTMAPK1HDAC3HDAC4HDAC1
	SCHEMBL8324505	0.83	MAPT (0.66)	MAPTMAPK1HDAC3HDAC4HDAC1
	SCHEMBL8996654	0.82	MAPT (0.64)	MAPTMAPK1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.