SCHEMBL9308820

SCHEMBL9308820

CCN(CC)c1ccc(N=Nc2ccc(N=Nc3nc4ccccc4s3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INSR P06213 4/20 0.73
MAPT P10636 11/20 0.54
NPC1 O15118 7/20 0.54
KMT2A Q03164 6/20 0.54
MEN1 O00255 5/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
CYP3A4 P08684 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C19 P33261 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
RAB9A P51151 6/20 0.48
APP P05067 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 2/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 2/20 0.42
NFKB1 P19838 2/20 0.42
NFKB2 Q00653 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24046417 1.00 INSR (0.73) INSRMAPTNPC1KMT2AMEN1
SCHEMBL24046415 0.90 INSR (0.64) INSRMAPTNPC1KMT2AMEN1
SCHEMBL3437502 0.89 INSR (0.59) INSRMAPTNPC1KMT2AMEN1
SCHEMBL3437405 0.89 INSR (0.59) INSRMAPTNPC1KMT2AMEN1
Bromide SCHEMBL3194701 0.87 INSR (0.60) INSRMAPTNPC1KMT2AMEN1
SCHEMBL24046402 0.87 INSR (0.60) INSRMAPTNPC1KMT2AMEN1
Bromide SCHEMBL3194708 0.87 INSR (0.60) INSRMAPTNPC1KMT2AMEN1
SCHEMBL8390776 0.85 INSR (1.00) INSRMAPTNPC1KMT2AMEN1
SCHEMBL8390778 0.85 INSR (1.00) INSRMAPTNPC1KMT2AMEN1
SCHEMBL16107254 0.84 INSR (0.57) INSRMAPTNPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10690953-B2 Polarizing plate and circularly polarizing plate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-06-23 US disclosed
US-20180067348-A1 POLARIZING PLATE AND CIRCULARLY POLARIZING PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-08 US disclosed
US-20180067348-A1 POLARIZING PLATE AND CIRCULARLY POLARIZING PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-08 US disclosed
US-5332521-A Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO., LTD. (JP) 1994-07-26 US disclosed
EP-0352637-B1 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO (JP) 1994-03-30 EP disclosed
US-5200108-A Flexible substrates supporting layer of liquid crystal material and non-liquid crystalline polymer IDEMITSU KOSAN CO., LTD. (JP) 1993-04-06 US disclosed
EP-0352637-A2 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-01-31 EP disclosed