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Sugi Predict / Compounds / SCHEMBL3437405

SCHEMBL3437405

SCHEMBL3437405

CCN(CC)c1ccc(N=Nc2ccc(N=Nc3ccc(N=Nc4nc5ccccc5s4)cc3)c(C)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ INSR P06213 5/20 0.59
▸ MAPT P10636 12/20 0.45
▸ KMT2A Q03164 7/20 0.45
▸ NPC1 O15118 7/20 0.45
▸ SMN1; SMN2 Q16637 7/20 0.45
▸ MEN1 O00255 6/20 0.45
▸ CYP3A4 P08684 3/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ CYP2D6 P10635 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ NPSR1 Q6W5P4 1/20 0.45
▸ RAB9A P51151 6/20 0.43
▸ L3MBTL1 Q9Y468 3/20 0.43
▸ APP P05067 1/20 0.43
▸ TDP1 Q9NUW8 4/20 0.41
▸ MAPK1 P28482 4/20 0.41
▸ ATM Q13315 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MCL1 Q07820 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9308820 0.89 INSR (0.73) INSRMAPTKMT2ANPC1SMN1; SMN2
SCHEMBL24046417 0.89 INSR (0.73) INSRMAPTKMT2ANPC1SMN1; SMN2
SCHEMBL13612619 0.88 MAPT (0.48) INSRMAPTKMT2ANPC1SMN1; SMN2
SCHEMBL24046413 0.82 INSR (0.46) INSRMAPTKMT2ANPC1SMN1; SMN2
SCHEMBL19760855 0.81 INSR (0.48) INSRMAPTKMT2ANPC1SMN1; SMN2
SCHEMBL3437502 0.81 INSR (0.59) INSRMAPTKMT2ANPC1SMN1; SMN2
SCHEMBL24046421 0.81 INSR (0.45) INSRMAPTKMT2ANPC1SMN1; SMN2
SCHEMBL24046415 0.80 INSR (0.64) INSRMAPTKMT2ANPC1SMN1; SMN2
SCHEMBL23236821 0.80 RAB9A (0.47) MAPTKMT2ANPC1SMN1; SMN2MEN1
SCHEMBL24046402 0.80 INSR (0.60) INSRMAPTKMT2ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160280999-A1 POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF FUJIFILM CORPORATION (JP) 2016-09-29 — — US disclosed
US-20160280999-A1 POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF FUJIFILM CORPORATION (JP) 2016-09-29 — — US disclosed
US-9382481-B2 Polarizing film, display device and production process thereof FUJIFILM CORPORATION (JP) 2016-07-05 — — US disclosed
US-9382481-B2 Polarizing film, display device and production process thereof FUJIFILM CORPORATION (JP) 2016-07-05 — — US disclosed
US-9011988-B2 Liquid-crystal compound, liquid-crystal composition, light absorption anisotropic film, and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-04-21 — — US disclosed
US-9011988-B2 Liquid-crystal compound, liquid-crystal composition, light absorption anisotropic film, and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-04-21 — — US disclosed
US-8927070-B2 Dichroic dye composition, light absorption anisotropic film, and polarizing element FUJIFILM CORPORATION (JP) 2015-01-06 — — US disclosed
US-8927070-B2 Dichroic dye composition, light absorption anisotropic film, and polarizing element FUJIFILM CORPORATION (JP) 2015-01-06 — — US disclosed
US-8865275-B2 Light absorption anisotropic film, polarizing film, process for producing the polarizing film and display device using the polarizing film FUJIFILM CORPORATION (JP) 2014-10-21 — — US disclosed
US-8865275-B2 Light absorption anisotropic film, polarizing film, process for producing the polarizing film and display device using the polarizing film FUJIFILM CORPORATION (JP) 2014-10-21 — — US disclosed
US-20110177315-A1 DICHROIC DYE COMPOSITION, LIGHT ABSORPTION ANISOTROPIC FILM, AND POLARIZING ELEMENT FUJIFILM CORPORATION (JP) 2011-07-21 — — US disclosed
US-20110177315-A1 DICHROIC DYE COMPOSITION, LIGHT ABSORPTION ANISOTROPIC FILM, AND POLARIZING ELEMENT FUJIFILM CORPORATION (JP) 2011-07-21 — — US disclosed
US-20110051052-A1 POLARIZING FILM, LAMINATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 — — US disclosed
US-20110051052-A1 POLARIZING FILM, LAMINATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 — — US disclosed
US-20100182543-A1 LIQUID CRYSTALLINE COMPOSITION AND LIGHT ABSORPTION ANISOTROPIC FILM, A POLARIZING ELEMENT AND A LIQUID CRYSTAL DISPLAY DEVICE, EACH EMPLOYING THE SAME FUJIFILM CORPORATION (JP) 2010-07-22 — — US disclosed
US-20100182543-A1 LIQUID CRYSTALLINE COMPOSITION AND LIGHT ABSORPTION ANISOTROPIC FILM, A POLARIZING ELEMENT AND A LIQUID CRYSTAL DISPLAY DEVICE, EACH EMPLOYING THE SAME FUJIFILM CORPORATION (JP) 2010-07-22 — — US disclosed
US-20100134726-A1 POLARIZING ELEMENT AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-06-03 — — US disclosed
US-20100134726-A1 POLARIZING ELEMENT AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-06-03 — — US disclosed
US-20090274853-A1 DICHROIC DYE COMPOSITION FUJIFILM CORPORATION (JP) 2009-11-05 — — US disclosed
US-20090274853-A1 DICHROIC DYE COMPOSITION FUJIFILM CORPORATION (JP) 2009-11-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274853-A1 DICHROIC DYE COMPOSITION C1S, CDY1; CDY1B, CRY1 INSR 1209/4885MAPT 2754/4885KMT2A 2439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.